Warfarin, Insulin, Anti-platelet Agents, and Hypoglyemic Medications in the Elderly May Warrant a Population Health Management Program to Reduce Avoidable Hospitalizations

Jaan Sidorov

Posted 11/28/11 on The Disease Management Care Blog

100,000.

That’s how many persons aged 65 years or more are seen in U.S. emergency rooms and then hospitalized every year because of an adverse drug event.

Writing in the New England Journal, Daniel Budnitz and colleagues report data from the “National Electronic Injury Surveillance System – Cooperative Adverse Drug Event Surveillance” (NEISS-CADES) project.  The Disease Management Care Blog never heard of it either, but it’s a consortium of 58 typical U.S. hospitals that are participating in an ongoing observational research project.  Whenever a physician blames a drug for an emergency room (ER) visit, trained chart reviewers go through the medical record.  From 2007 through 2009, there were 12,666 drug-related ER visits in the NEISS-CADES hospitals, which extrapolates to over 265,000 in the U.S.  More than a third required hospitalization, which rounds to approximately 100,000.

Continue reading “Warfarin, Insulin, Anti-platelet Agents, and Hypoglyemic Medications in the Elderly May Warrant a Population Health Management Program to Reduce Avoidable Hospitalizations”

Insulin and Increased Cancer Risk

WILLIAM H. BESTERMANN

“Traditional wisdom can be long on tradition and short on wisdom”

Warren Buffet

My colleagues have asked me about an article in Diabetes Care that shows roughly a 40% reduction in cancer risk in patients who are on insulin and treated concurrently with metformin.  The reduction in cancer risk was attributed to beneficial effects of metformin. This information is not surprising. We have already gone into the metformin and cancer story in this space.

Continue reading “Insulin and Increased Cancer Risk”