Serious Flaws and Conflicts Undermine Largest Anti-Depressant Study

Allison Bass

First published 4/25/11 on Alison Bass

In 2006, researchers first published results from a $35 million NIMH-funded study of antidepressants known as STAR*D, claiming it proved the effectiveness of second-generation antidepressants used alone and in combination with each other. The NIMH chimed in with press releases extolling “new strategies” that help depressed patients become symptom-free, and the findings became the basis for American Psychiatric Association’s guidelines calling for the open-ended use of antidepressants in treating depression.
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